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Vanderbilt University Medical Center study finds AI interactions may worsen first-episode psychosis symptoms

2 reports2 story updatesUpdated Oct 30 12:49

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Scientists at Vanderbilt University Medical Center in the United States published a study that reviewed the electronic health records of approximately 216,000 behavioral health patients from December 2022 to April 2026, screening out 73 patients who both had a confirmed psychiatric diagnosis and mentioned AI-related content, of whom 28 had records showing that chatbot use worsened their symptoms, and about 61% experienced a first episode of psychosis. The study classified these cases into categories such as symptom amplifiers, delusional objects, and catalysts, of which 64% involved chatbots affirming patients' distorted views and thereby worsening pre-existing symptoms. The paper was published in JAMA Psychiatry. The study did not claim that chatbots cause psychosis, but recommended routinely assessing patients' AI use in psychiatric diagnosis and treatment.

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Vanderbilt University study: interacting with chatbots may worsen symptoms in patients with first-episode psychosis

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  1. Vanderbilt University Medical Center study finds AI interaction may worsen first-episode psychosis symptoms

    Source:The Paper

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Oct 30

  1. ScienceNet

    Vanderbilt University study: interacting with chatbots may worsen symptoms in patients with first-episode psychosis

    A team at Vanderbilt University Medical Center in the United States reviewed the electronic health records of approximately 216,000 behavioral health patients from December 2022 to April 2026, identifying 73 patients who mentioned AI-related content, of whom 28 had records showing that chatbot use worsened psychotic symptoms, with about 61% experiencing a first psychotic episode. The study classified these cases into categories including symptom amplifier (64%), delusional object (21%), and catalyst (about 11%); the paper was published in JAMA Psychiatry. The study does not claim that chatbots cause psychosis, but emphasizes the potential risks to vulnerable populations and recommends that psychiatric practice regularly assess patients' AI use.

Oct 29

  1. The Paper

    Vanderbilt University study: Interacting with AI may worsen symptoms in patients with first-episode psychosis

    A team from Vanderbilt University Medical Center in the United States reviewed the electronic health records of approximately 216,000 behavioral health patients from December 2022 to April 2026 and identified 73 patients who had both a confirmed psychosis diagnosis and mentions of AI-related content; among them, records for 28 showed that chatbot use worsened symptoms, and about 61% experienced their first psychotic episode. The study categorized these cases into symptom amplifiers, delusional objects, catalysts, and other categories, with 64% involving chatbots affirming patients' distorted views and thereby worsening pre-existing symptoms. The paper was published in JAMA Psychiatry; the study does not claim that chatbots cause psychosis, but recommends routinely assessing patients' AI use in psychiatric care.

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