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The Anthropic team used 950 Claude agents running in parallel for 21 hours, consuming about 210 million tokens, scanning over 200,000 reverse transcriptases, screening out 3,500 candidate systems and locking in 20 key targets, and discovered a previously uncharacterized enzyme system in giant phage DNA, named ART (array-associated reverse transcriptase system). ART contains reverse transcriptase, companion genes and regularly spaced DNA repeats, with a structure similar to CRISPR arrays; preliminary experiments show that its array expresses a set of distinct short RNAs. The human team only provided the initial exploration prompt; all wet-lab experiments were completed by human scientists, using tools including Claude Science and Claude Code. There are currently no further developments.
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