Anthropic discloses 211 scorpion venom neurotoxin-binding proteins designed by Claude

Ben's Bites

Anthropic launches personal agent app Duet

Anthropic has launched its personal agent/assistant app Duet as a research preview, currently available only on mobile in the United States. Anthropic also reported that of 211 anti-scorpion neurotoxin protein binders designed by Claude, 17 met its experimental binding criteria.

TMTPost · AGI

Edge AI Daily Morning Brief: Meta Raises AI Spending, Anthropic Prospectus, and OpenAI Joins Google Cloud

Meta's third-quarter capital expenditure was $34.9 billion, with full-year guidance narrowed to $135 billion to $145 billion; Anthropic's prospectus shows revenue of approximately $16.3 billion in the first half of 2026, a year-over-year surge of 1,382%, and a net loss of $80.7 billion. On October 21, OpenAI announced that it will bring its frontier models and Codex to Google Cloud's Model Garden, opening in the coming weeks, and enterprise customers can pay using their Google Cloud spending commitments.

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Phoenix Tech

Anthropic publishes Claude protein design study: 310,000 designs generated in 64 hours, 17 validated experimentally

Anthropic has published a biology study in which Claude autonomously invoked 12 protein design tools within 64 hours, generating 318,484 candidate protein designs targeting 5 scorpion venom neurotoxins, and screened out 211 to be handed over to Adaptyv Bio and Twist Bioscience laboratories for validation, with 17 ultimately meeting the preset binding criteria. Among them, the dissociation constants KD of Cn2-B1 and Cn2-B2 targeting the Cn2 toxin reached single-digit nanomolar levels, but the experiments only validated binding ability and have not yet proven that they can neutralize the toxin or provide protection in vivo. The research team set the goals and screening rules; after Claude ran autonomously for 24 consecutive hours, the researchers added 4 additional prompts; the computational design phase consumed a total of about 10,000 GPU hours; and all 211 candidate designs and experimental data have been made public.

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Claude autonomously designed 17 molecules that bind scorpion venom neurotoxins in Claude Science

In Anthropic's Claude Science environment, Claude autonomously completed an entire round of protein design as an agent: it selected the attack sites on scorpion venom neurotoxins on its own, drove 12 protein design programs, set scoring thresholds, and selected 180 molecules from the 318,484 generated to send for physical synthesis; of the 211 designs tested by Adaptyv Bio and Twist Bioscience, 17 successfully bound the target toxin. The request was made by Citrini Research, a financial firm with no laboratory or protein expertise. Anthropic did not call it an antivenom serum because the tests needed to support that claim have not yet been conducted.

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