OpenAI releases the GPT-Rosalind-6 system card addendum, offering restricted access for biological research
OpenAI releases the GPT-Rosalind-6 system card addendum. This model uses the same set of weights as GPT-6 Astra, with no new training data or post-training added, and is provided only through trusted access to vetted research institutions, enterprises, and government partners. At the highest reasoning budget, MedChemBench v7 averages 49.6% (GPT-Rosalind-5.5: 28.9%), GeneBench Pro v13 single-attempt success rate is 37.7% (previous generation: 16.7%), and LifeSciBench Gold average score is 61.3% (previous generation: 44.0%). Under the Preparedness Framework, this release is rated High capability in the biological and chemical domains, below the Critical threshold; rated Critical in the cybersecurity domain; and below High in AI self-improvement.
Why read thisThe system card discloses specific scores and threshold gaps for biological-domain capability evaluations, which can be used to understand the openness boundary of frontier models in dual-use research.



