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The team led by Dai Qionghai at Tsinghua University and the team led by Dai Pu at Chinese PLA General Hospital have developed an ultra-light wireless mesoscopic microscope, Airscope. Weighing only 1 gram, the device can record neural activity in the mouse cerebral cortex within a 6-millimeter field of view at a single-cell resolution of 4 to 6 micrometers, capturing more than 8,500 neurons simultaneously in a single mouse—25 times that of existing devices of the same type. The device uses only 4 aspheric lenses and achieves on-device compression through a 2-megapixel image sensor, enabling wireless transmission of megapixel-level images and freeing it from cable constraints. The results were published online in Nature on the 19th. The team has used it to record cortical activity in multiple mice across a 5-square-meter natural habitat and a large maze with 32 endpoints.
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Oct 21
Jiwei.com
A team at Tsinghua University has developed Airscope, a 1-gram wireless mesoscopic microscope, with the results published in Nature
The team led by Dai Qionghai of Tsinghua University and the team led by Dai Pu of Chinese PLA General Hospital have developed Airscope, a wireless mesoscopic microscope weighing only 1 gram. It can record neural activity in the mouse cerebral cortex within a 6-millimeter field of view at 4 to 6 micrometers single-cell resolution, and a single mouse can have more than 8,500 neurons recorded simultaneously, 25 times that of existing devices of the same type. The device uses only 4 aspheric lenses and achieves on-device compression through a 2-megapixel image sensor, enabling wireless transmission of megapixel-level images and freeing it from cable constraints. The results were published online in Nature on the 19th, and the team has used it to record cortical activity in multiple mice in a 5-square-meter natural habitat and a large maze with 32 endpoints.