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Google Blog更新于 10月13日 11:32

Google 推出 SynthID Bio,为 AI 设计的蛋白质加水印

SynthID Bio watermarks AI-designed proteins

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Google 发布 SynthID Bio,可在 AI 生成的蛋白质序列和预测 3D 结构中嵌入不可感知且可验证的水印。实验室测试显示,加水印的设计在多个目标蛋白上与未加水印版本的表现和天然多样性相当,为生物安全和开放科学数据库提供溯源层。

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Google 把水印从文本图像扩展到 AI 设计的蛋白质序列与结构,读者可了解生物设计溯源这一新方向。

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Sep 30, 2026

Today, we’re introducing SynthID Bio, a new technology that watermarks AI-designed proteins while preserving their biological function.

SynthID Bio embeds an imperceptible, verifiable watermark directly into biological designs, such as AI-generated protein sequences and predicted 3D structures.

In laboratory tests across target proteins, our watermarked designs successfully matched the performance and natural diversity of unwatermarked versions. This creates a vital provenance layer to strengthen biosecurity and preserve the integrity of open scientific databases.

Visualization of the predicted structure of our watermarked VEGF-A protein binder with watermark signal indicated by color for each amino acid.

Binding affinity, measured as KD, comparing non-watermarked and watermarked protein designs across three targets. Lower indicates stronger binders.

On 7PPA, we show the AF3 predicted structure (left), the ground truth structure (middle), and the watermarked structure (right).

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Google Blog