Google DeepMind 用 Google Antigravity 加速抗菌肽发现
Google DeepMind 介绍其智能体开发平台 Google Antigravity 如何加速抗菌肽(AMP)的发现,把原本分散在多个数据库的检索压缩到一次会话中,并借助 ProtNLM 模型扫描 UniProt 中数百万条未表征蛋白质。文中展示生物学家用该平台找到一个对呼吸道感染病原体有预测活性的新型抗菌肽候选物,该候选物目前正在进行湿实验验证。Antigravity 还内置了 Biomolecular Structure Viewer,可在同一工作区内查看 AlphaFold 预测结构并与智能体共享 3D 视觉状态。
ies in competing bacteria, from cell envelopes to essential intracellular machinery, making it difficult for pathogens to develop resistance. The exponential growth of genomic and metagenomic sequencing has populated global databases with billions of natural amino acid sequences. This pool of natural data has already produced globally used bacteriocins like Nisin, alongside recent genome-mined breakthroughs such as Darobactin, Dynobactin, and Lariocidin. Many, however, remain locked within the u
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